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The first, second and third generation test tubes are completely different! It's not an upgrade, it's a division of labor
Source: lelaiwaPublished: 2026-09-12
This article is compiled and published by the lelaiwa team. Unauthorized reproduction is prohibited. For ongoing updates on fertility preparation, IVF, and overseas or U.S. childbirth, scan the consultant's QR code on the right to get free updates, or contact lelaiwa for free consultation anytime.

When implementing IVF technology, it is often easy to fall into the misunderstanding

that the higher the algebra, the more advanced the technology.

Many couples intending to conceive blindly pursue the "third-generation IVF technology", believing that the first generation has fallen behind, the second generation is more common, and the third generation is the most outstanding.

In order to "pursue a better baby", some couples even spent tens of thousands or even hundreds of thousands of yuan to forcibly choose the third-generation technology. In the end, they found that the technology was not suitable for their own situation, which not only wasted precious embryo resources, but also took a lot of time. Comprehensive analysis: The first, second and third generations of IVF technologies are not simple technological iterative upgrades, but each has its own unique application scenarios and responsibilities!

There are no absolutely excellent algebra options, only the IVF solution that best suits your physical condition.

01 Please core points:

First generation IVF technology: helps sperm and eggs meet (mainly solves infertility caused by female factors)

Second generation IVF technology: helps eggs and sperm combine (mainly solves infertility caused by male factors)

Third generation IVF technology: screening healthy embryos (mainly solves problems such as genetic diseases, elderly maternity, fetal arrest, etc.) is

not that the third generation is better than the second generation, the second generation is better than the first generation,

but the symptomatic choice

02 The first generation IVF technology| Naturally preferred, it is suitable for the group closest to the natural conception process

-fallopian tube blockage, adhesion or hydroponding

-ovulation disorder, polycystic ovary syndrome

-endometriosis

-unexplained infertility, and the basic conditions of sperm and eggs of both couples are normal. Brief description of the

principle

In a laboratory environment, sperm and eggs are placed together, allowing them to combine freely to achieve natural fertilization.

This process is highly similar to the logic of natural pregnancy, but provides an opportunity for them to meet outside the body.

Advantages

-closest to the natural conception process

-no manual forced intervention in the fertilization process

-relatively low cost and simple process

-small probability of embryo damage

Not applicable.

Men's sperm quality is extremely poor, with severe oligospermia symptoms, and sperm cannot penetrate on their own. Eggs.

03 Second generation IVF technology| Single sperm injection, which solves the problem of male infertility, is

suitable for the population

-the male has severe oligospermia, weak spermia, and abnormal spermia

-the sperm vitality is extremely low and the number is rare

-the quality of the sperm on the day of egg retrieval

-a brief description of the principle of failure in previous fertilization attempts

The

doctor will carefully select a high-quality sperm and inject it directly into the egg to force fertilization.

If the first-generation technology is compared to "free love"

, the second-generation technology can be regarded as "manual matchmaking and precise matching."

Answer to common doubts: Are babies born with second-generation technology unhealthy?

Authoritative answer: Not so.

The second-generation technology provides artificial assistance in fertilization methods, and the baby's genes, IQ, physique and other aspects are no different from those of the first-generation technology. There is no significant difference in health between natural conception and conception through assisted reproductive technology.

Based on comprehensive big data tracking research, we confirm that the health status of babies born through second-generation IVF technology is no different from that of naturally born babies.

04 The third generation of IVF technology| Embryonic genetic screening to achieve accurate eugenics

(Special reminder: those with non-specific needs do not need to be considered)

·Elderly women over 35 years old

who are planning to conceive·Those who have experienced multiple fetal stops or failed embryo transfer

·Chromosomal abnormalities in both couples

·Couples with a history of family genetic diseases

·Summary of technical principles for those who have encountered multiple poor embryo quality or biochemical pregnancies

.

Compared with the first and second generation technologies that only complete the basic steps of fertilization and embryo culture, the third generation of IVF technology has added a key link on this basis: comprehensive chromosome screening of embryos.

Purpose of screening-

to exclude unhealthy embryos such as chromosomal abnormalities, deletions, and duplication

-to preserve the core advantages of high-quality embryo technology with complete and normal chromosome structure

-to effectively reduce the risk of fetal arrest

-to reduce the incidence of abortion.

Clarify common cognitive misunderstandings

: The third generation technology is more advanced, so children born are smarter

Facts: The third generation technology is mainly designed to improve safety and stability, and is specially designed for high-risk pregnant people

.

When choosing IVF technology, do not fall into the misunderstanding of "the higher the price, the better, the newer the better".

Choosing the most suitable test tube algebra and treatment plan based on your actual situation is far more important than blindly investing money, unnecessary anxiety, or trying to follow suit. Such a rational choice will help you realize your pregnancy dream faster and smoothly usher in the arrival of a new life.

May every woman who works tirelessly on the road to pregnancy find the right direction, reduce unnecessary twists and turns, and finally usher in a happy pregnancy of her own.


For more on fertility preparation, second/third-generation IVF, and overseas, U.S., Thailand, Malaysia, America or Cambodia IVF, scan the QR code on the right or call lelaiwa's hotline+852 6145 8043!
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