How to treat people with polycystic ovary syndromebefore undergoing IVF?

On the road to pursuing their childbearing dreams, patients with polycystic ovary syndrome (PCOS) often face more challenges. This common endocrine disorder not only affects women's menstrual cycle and health

Fertility ability has added some uncertainty to the modern medical technology of test-tube fertilization. However, just as every dark cloud is inlaid with silver, challenges also contain opportunities. Through careful conditioning and

Prepare, PCOS patients can also welcome the dawn of IVF and embark on their own journey of gestation.

Before starting this special IVF journey, patients need to fully understand their condition, communicate in depth with doctors, and jointly develop a personalized conditioning plan. From the perspective of lifestyle

From the adjustment of mental state to the choice of professional treatment, every step is crucial and will become a solid foundation for your path to success. Next, let us explore this careful conditioning together

Journey

Below, let's take a detailed look at what problems polycystic ovaries cause and how to regulate them before doing test tubes.

What problems does polycystic ovary syndrome cause?

n 1. Irregular menstruation and anovulation or oligovulation

Women with PCOS often have irregular cycles, sporadic menstruation, low volume or amenorrhea. They can also have excessive menstruation and unpredictable intermenstrual bleeding, which affects normal life. In a few cases, PCOS

The patient has a regular menstrual cycle, but cannot ovulate normally due to disorders in follicular development and maturation.

2. Endometrial hyperplasia

Due to long-term anovulation and lack of the antagonistic effect of progesterone, the endometrium is stimulated by estrogen for a long time, which is prone to hyperplasia and may even develop into endometrial cancer. For concomitant

Treatment for patients with PCOS with endometrial hyperplasia usually includes lifestyle adjustments, medication (such as hormone therapy), and surgery (such as endometrial removal).

3. Increased risk of spontaneous abortion

Patients with PCOS have an increased risk of spontaneous abortion after pregnancy due to problems such as sex hormone disorders, abnormal glucose metabolism, insulin metabolism, lipid metabolism, and abnormal immune factors. Studies have shown that patients with PCOS

Patients need closer monitoring and management during pregnancy to reduce the risk of spontaneous abortion.

4. Luteal phase deficiency (LPD)

Due to persistent anovulatory, ovarian function decreases in patients with PCOS, which may lead to corpus luteal dysfunction. Luteal dysfunction is manifested by poor endometrial secretion and shortened luteal phase, which may lead to menstruation

Hemorrhage and menstrual disorders in the second half. For corpus luteal dysfunction caused by PCOS, treatment usually includes medical treatment (such as didrogterone tablets, letrozole tablets, etc.) and surgical treatment if necessary (such as laparoscopic

Lower ovarian perforation).

How to recuperate before entering the IVF cycle?

1. Weight Management

High hormone and insulin resistance arethe main causes of PCOS. Obesity not only affects the overall health of patients, but may also affect the success rate of IVF. Therefore, weight management is important for patients with polycystic ovary syndrome

is an important part before entering the IVF cycle. Patients are advised to follow healthy eating habits and consume enough protein, vitamins and minerals, while controlling sugar and fat intake. Daily hot

The recommended intake is controlled between 1200-1500 kcal to maintain a healthy weight. Performing moderate exercise, such as aerobic exercise such as jogging, brisk walking, swimming, yoga, etc., can help burn excess calories

Promote weight loss. It is recommended to exercise at least 3 times a week for at least 40 minutes each time. Regularly monitor weight changes and adjust diet and exercise plans in a timely manner to maintain a healthy weight range.

n 2. Emotional management

50%-80% of women with PCOS suffer from obesity, most of which are abdominal obesity. Due to the accumulation of excessive visceral adipose tissue, a large number of inflammatory factors are released and the body is in a chronic low-grade inflammatory state. Research

It indicates that depression is closely related to chronic low-grade inflammatory state, increased inflammatory factors TNF-α and IL-6, which can affect the level of neurotransmitters in the synaptic space of nerve cells, leading to depression, anxiety and other unhealthy conditions

Kang emotion. In addition, infertility, hirsutism, obesity, and other chronic diseases can reduce the patient's quality of life and cause psychological burden on patients, leaving patients in states such as anxiety and depression.

tTherefore,screening for anxiety and depressive symptoms should be performed when diagnosing PCOS to detect the presence of depression or anxiety in a timely manner. Adverse psychological problems can also affect physiological functions and aggravate the patient's endocrine system

Abnormal stress can make the condition worse.

You can reduce stress and avoid exacerbating emotional abnormalities by regular work and rest, quitting smoking and alcohol, and increasing exercise. At the same time, weight loss can effectively help patients build confidence and improve their quality of life. Home

Emotional support from people and friends can positively guidepatients with PCOS to relieve anxiety and improve self-perception.

3. Drug preparation

n

Compound oral contraceptives(COC) are the first-line drugs for PCOS. COC is mainly composed of estrogen and high-potency progesterone, which inhibits follicles by inhibiting follicle stimulating hormone (FSH) and luteinizing hormone

Development reduces the production of androgens. COC increases the level of sex hormone-binding globulin, thereby reducing free testosterone levels and reducing the peripheral effect of androgens. Currently commonly used clinical COCs such as

Marfulon or You Siming, etc.

In addition, before entering the IVF cycle, IVF fertility teacherswill also guide women to take contraceptives to downtune. This is mainly because women have a dominant follicle among several follicles every month. Through aspiration

Other follicles in the receiving ovary can grow, causing other follicles to apoptosis. Therefore, inhibiting the growth of dominant follicles can enable multiple follicles to develop evenly and synchronously and obtain more mature eggs when promoting oocyte retrieval. by

These eggs come from follicles that are about to disappear and die, so they will not overconsume the number of follicles and will not have any impact on the body.

In summary, polycystic ovary syndrome (PCOS) not only affects a woman's fertility, but may also lead to irregular menstruation, endometrial hyperplasia, increased risk of spontaneous abortion, and luteal dysfunction.

Therefore, early detection and early treatment are crucial for patients with PCOS. At the same time, measures such as improving lifestyle, adjusting eating habits, and strengthening physical exercise will also help improve PCOS

Symptoms and prevention-related complications.