Can elderly women avoid chromosomal abnormalities when undergoing IVF?

In modern society, as the childbearing age of women gradually delays, preparing for pregnancy among older women has become a hot topic. However, a major challenge facing older women when pregnant is the risk of chromosomal abnormalities

Risk increased. So, can IVF technology provide elderly women with a solution to avoid chromosomal abnormalities?

Why do chromosomal abnormalities occur when giving birth at an advanced age?

Chromosomes are the basic material that makes up the cell nucleus and the carrier of genetic material. The human body has23 pairs of chromosomes (22 pairs of autosomes +1 pair of sex chromosomes), and each pair of chromosomes will occur during meiosis.

Separate from each other and then enter different daughter cells. Different pairs of chromosomes or genetic factors combine freely. During the process of division and recombination, chromosome defects often occur due to the influence of various factors

Abnormality such as loss, translocation, increase in number or duplication causes chromosome abnormalities in the embryo.

The main causes of chromosomal abnormalities are

(1) Decrease in the quality of germ cells: As you age, the quality of women's eggs will gradually decrease and aging occurs. This aging can make egg cells more likely to emerge during fertilization and cell division

Problems such as genetic mutations, malformations and chromosomal abnormalities are occurring. According to research, the rate of egg chromosome abnormalities in older women is significantly increased. For example, a study by the U.S. Centers for Disease Control and Prevention (CDC) shows that 35-year-olds

Women older have a higher probability of chromosomal abnormalities than women aged 20-34.

(2) Chromosome non-disjunction: The ability of germ cells to divide in elderly women will also decrease, especially during meiosis or early mitosis in the fertilized egg, where a certain chromosome may not be disjunction.

Condition. This can lead to abnormalities in the number of chromosomes in the fetus after fertilization, common such astrisomy 21 and trisomy 18.

(3) External environmental impacts: If elderly pregnant women are exposed to external environmental impacts during pregnancy, such as radiation, environmental pollution, virus infections, etc., it can easily cause chromosome abnormalities during embryonic development

changes, causing chromosomal abnormalities in the fertilized egg.

If the chromosome of the embryo is abnormal, it will cause fetal arrest, abortion and other adverse conditions during pregnancy. Even if pregnancy is successful until delivery, problems such as neonatal defects or malformations will occur, such as mental retardation and developmental delay

or limb deformity, etc. A common chromosomal disease istrisomy 21 syndrome (Down syndrome), which is caused by an extra chromosome 21. Babies with Down syndrome will show intellectual impairment

It has characteristics such as a special face, cracked eyes and tilted upward. In addition, there are trisomy 13 syndrome, trisomy 18 syndrome, cat barking syndrome, etc.

Tip: The older the couple is, the higher the probability of chromosomal abnormalities, which will significantly increase the probability of birth arrest or birth defect babies and neonatal malformations. Therefore, it is recommended that both couples should

put the family planning on the agenda and fulfill the baby's dream as soon as possible.

So

can anolder womanavoid chromosomal abnormalities by doing IVF?

It is possible to avoid chromosomal abnormalities by doing IVF at an advanced age. Because the third generation IVF technology is currently used to assist pregnancy, it can effectively avoid chromosomal abnormalities and improve female pregnancy

Rate protects the health of future generations from the root cause and achieves excellent pregnancy and eugenics.

PGT-Mgene testing is an important core technology for the third generation of test-tube babies. For example,bydetecting the chromosome number and structure of the blastocyst, it analyzes and compares whether the embryo has chromosome deletions, duplication and ease

n

and other abnormalitiesdiagnose whether the embryo carries a genetic defect gene or a genetic mutation that causes a specific disease, and then select healthy and high-quality blastocysts from it for transplantation, which can effectively avoid the occurrence of chromosomal abnormalities in the embryo

It often leads to fetal arrest, abortion, etc., while protecting the health of future generations.

Couples who have had embryonic chromosome abnormalities that led to miscarriage have a higher probability of having this problem when they become pregnant again. Therefore, it is recommended to use scientific methods to assist pregnancy. Only in this way can we effectively avoid pregnancy

Fetal arrest, abortion or deformed baby, etc.

During pregnancy, expectant mothers should also maintain good living habits, avoid staying up late, regular work and rest schedules, go to bed early and wake up early; make a reasonable diet, ensure balanced nutrition, eat more vegetables and fruits, and high-quality

Proteins, etc., provide sufficient nutrients for the growth and development of the fetus; stay away from radiation and harmful chemical substances, maintain a happy and comfortable mood, which is conducive to the growth of the fetus and avoids fetal arrest, risk of abortion.