tIntrauterine Insemination (IUI Technology)

When a woman conceives naturally, sperm enters the uterus from the vagina through the cervix (a narrow site at the base of the uterus) and then into one side of the fallopian tube. If the sperm reaches the fallopian tube shortly after the ovary releases the egg, then the sperm

and the egg will meet and combine (fertilization) in the fallopian tube.

The cervix is a natural barrier that limits the number of sperm entering the uterus. This means that only a small portion of the sperm ejected by a man actually enters the fallopian tube. Intrauterine artificial insemination (IUI) is a method of inducing intrauterine insemination that occurs before and after ovulation in women

Surgery in which sperm is injected into the uterus through the cervix. This technology shortens the time it takes for sperm to reach the fallopian tube and allows more sperm to meet the egg. The purpose of this technology is to increase a woman's chances of getting pregnant.

When is IUI helpful?

There are many reasons why partners have difficulty conceiving, and IUI can be helpful to some of them. Unknown cause: IUI is most often applied when a partner becomes infertile due to unknown reasons. Women who are infertile will take some medicines (oral

Take or inject), so that multiple eggs in the ovaries of the body can develop and mature at the same time. The purpose of this process is to combine more sperm with more eggs, thereby increasing the odds of pregnancy.

Cervical stricture or abnormality: Some women have scars on the cervix that prevent sperm from entering the uterus from the vagina. IUI also applies to this situation. Some have undergone cervical surgery (cryosurgery, cone biopsy, and electrocoil

resection [LEEP], etc.) This may occur in women. IUI can also be used when the shape of a woman's uterus is abnormal and hinders sperm transport.

n

Abnormal sperm transport: IUI can also be used if the male partner of both partners cannot erect, cannot maintain an erection, cannot ejaculate effectively, or cannot ejaculate at all. For example, retrograde ejaculation refers to ejaculation during male orgasm

Fluid does not eject forward from the urethral orifice, but flows backward into the bladder. Past surgeries or diseases such as diabetes can cause retrograde ejaculation. Similarly, IUI is also suitable for men with abnormal urethral orifice (penile opening).

tAnovulation (ovulation arrest): In most cases, women who ovulate irregularly can also become pregnant through sexual intercourse. IUI can sometimes be helpful. Preserving fertility: Men undergoing vasectomy, testicular surgery

Before or radiotherapy/chemotherapy for cancer, sperm can be collected and frozen (cryopreserved) for later use. Sperm can be thawed for IUI in the future.

Third-party assisted reproduction: IUI is also performed when both partners use sperm that is not a male partner. This is called outmating artificial insemination (DI). When the male partner has no sperm, the quality of the sperm is so low that the sperm cannot be used

DI is performed at conception or when in vitro fertilization is not possible. DI can also be used if the man is diagnosed with a genetic disease and does not want to pass it on to his child. Single women or lesbians who want children also

DI can be considered.

How to collect sperm?

Sperm required by IUI can be collected in several ways. The most common case is that men masturbate and then send their semen to sterile cups or plastic cups provided by a doctor's office or andrology laboratory (a laboratory specializing in men's health issues)

in. You can also use a special condom provided by your doctor to collect sperm during sexual intercourse. If a man has symptoms of retrograde ejaculation, the laboratory can also obtain sperm from the urine he collects. For there is still a pesticide after application

For men with ejaculatory difficulties and men with spinal cord injuries, they can expel sperm through vibration stimulation or electroejaculation. Vibration stimulation is usually performed in a doctor's office and requires the use of a handheld vibration equipment. Electricity

Ejaculation is a process that uses electrical stimulation to promote ejaculation. For men with complete spinal cord injuries, electroejaculation usually takes place in the doctor's office, while men with incomplete spinal cord injuries require anesthesia in the operating room

Electroejaculate after being drunk. For more information on these techniques, please refer to the ASRM Patient Guide,"Surgical Sperm Extraction Techniques for Patients with Spinal Cord Injury." r

How does IUI do it?

After doctors collect a semen sample, they will "wash" it in the laboratory to concentrate the sperm and remove semen (semen can cause severe cramps in women). This process takes about 2 hours. IUI will be in the female row

Before and after the egg stage. IUI surgery is relatively simple and only takes a few minutes after the semen sample is prepared. After the woman lies on the examination table, the clinician places a speculum into the vagina to observe the cervix. One catheter (stenosis

tube) is inserted into the uterus through the cervix, and then slowly injected with a washed semen sample. The process is usually painless, but some women may experience mild cramps. Some women may

after IUI

Petechial bleeding will occur for 1-2 days.

Will IUI succeed?

The success rate of IUI depends on the root cause of the patient's inability to have children. IUI is most suitable for patients with unexplained infertility, women whose cervix restricts the passage of sperm, and men who cannot effectively ejaculate. For example, for no

n

For infertile cases with known causes, the pregnancy rate after IUI is twice that without treatment. For men with oligospermia or severely abnormal sperm, and with severe fallopian tube disease, moderate to severe endometriosis, and

For women with a history of pelvic (lower abdominal) infections, IUI is not as effective. Other fertility treatments are more effective for these patients. Overall, if fresh or frozen sperm can be used for insemination every month, the success rate

will be higher. The success rate depends on whether fertility drugs are used, the woman's age, infertility diagnosis and other factors.

Is IUI risky?

If a woman takes fertility drugs that increase the number of ovulations during IUI, her chances of conceiving twins, triplets, or multiple births are higher than if she did not take the medication. IUI does not increase the risk of birth defects. Whether it's nature

Pregnancy or pregnancy through IUI, 2%-4% of newborns will develop birth defects. The risk of infection due to IUI is small.