"I checked the semen, there is no problem!"
,,“”.However, when the wife has gone through multiple promotion and egg retrieval, but has never been able to obtain high-quality embryos or repeated transplants fail, a simple "semen routine" report often cannot explain all the difficulties.
“”,(“”,“”).However, modern reproductive medicine has found that what affects the quality of embryos and the outcome of test tubes is the "intrinsic quality" and "practical ability" of sperm. The following three inspections are the key to assessing these in-depth capabilities, and they are indispensable.
The first key: semen routine and morphological analysis-clearly see "strength" and "appearance"
This is the most basic step, but it must be done correctly and understood.
This is the most basic step, but it must be done correctly and understood properly.
What does it check?(),(),,“”.Malformed sperm (abnormal head, neck, and tail) have difficulty completing the task of penetrating the egg shell.
Why it’s necessary to do this:.If the number or vitality of sperm is seriously insufficient, or the deformity rate is extremely high, reproductive doctors will usually decisively recommend the use of second-generation in vitro fertilization technology (ICSI), or "intracytoplasmic single sperm injection", in which an embryologist selects a suitable shape. The sperm is injected directly into the egg to ensure fertilization. If you choose this wrong step, it may lead to the annihilation of the entire army.
The second key: Sperm DNA fragmentation rate (DFI) testing-assessing the integrity of the "genetic blueprint"
This is the most frequently ignored test that has a fatal impact on embryo quality.
,.You can think of DNA as the design blueprint for life.
What does it check?(DNA),.Even if a sperm is full of vitality and complete shape, if the "blueprint" it carries is damaged, the embryo formed by it can easily be arrested or aborted in early development.
Why it’s necessary to do this:DFI,.This is a common situation in clinical practice: a lot of eggs are taken and the fertilization rate is acceptable, but the embryos are just not developing well and the failure rate of raising cysts is high. When you check the man's DFI, it often exceeds 25%(normally it should be less than 15%). This explains why the "seeds" seem to have been planted, but they cannot produce healthy "buds".
,,,.Inspection found that his DFI was as high as 38%. After 3 months of antioxidant treatment and life adjustments, the DFI dropped to 19%. Following a subsequent promotion of expulsion, the quality of the obtained embryos was significantly improved, and the transfer was successful.
The third key: sperm acrosome function testing-testing the ability to "overcome difficulties"
This is the "last hurdle" test of whether the sperm can successfully combine with the egg.
This is the “final test” to determine whether the sperm and egg can successfully combine.
What does it check?“”,().The acrosome reaction test is to see whether sperm can normally release these enzymes when needed, thereby "opening" the door to the egg.
Why it’s necessary to do this:,,(ICSI),,.This test can directly explain the problem of "fertilization disorders".
,(IVF),.After acrosome function testing, the activity was found to be extremely low. It was adjusted to ICSI technology in a timely manner, and sperm function was improved in a targeted manner, and usable embryos were successfully obtained in subsequent cycles.
Summary: There are three inspections, none of which can be missing
In summary: All three inspections are necessary. None of them can be omitted.