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IVF egg retrieval is not the more the better!
Source: LelaiwaPublished: 2024-12-22
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1. The relationship between the number of oocytes retrieved and the success rate

Before egg retrieval, ovulation promotion operations need to be performed. If you want to obtain more eggs, you often need to use a large dose of ovulation inducing drugs, which will cause a significant increase in the woman's own estrogen level, which will lead to a pair

The receptivity of the endometrium has an impact, that is, the endometrium's ability to accept the embryo decreases. It can be seen that excessive number of oocytes retrieved will have adverse effects on embryo implantation and lead to a decrease in the success rate.

In 2011, statistical analysis from the British National Database confirmed this view. After analyzing 400,135 fresh IVF cycles, it was found that when the average number of eggs retrieved was about 15, live births were

Rates can reach higher values. When the number of eggs retrieved exceeds 15, the more eggs retrieved is not the better.

Disadvantages of too many oocyte retrieval

When the number of oocyte retrieved is too high, the amount of ovulation-inducing drugs will usually increase accordingly, which will increase the risk of developing ovarian hyperstimulation syndrome after egg retrieval. In addition, large doses of ovulation promotion drugs

Substances will increase the burden on the ovaries, decrease the quality of the oocyte, and ultimately affect the treatment results.

In addition, most of the women with a large number of oocytes retrieved are young. They often only need 1 - 2 embryos to conceive, and the rest of the embryos are frozen in liquid nitrogen tanks. The probability of being thawed again is low, so

Causes a large waste of embryo resources. According to literature reports, in ovulation promotion cycles using high-dose drugs, the egg utilization rate is only 6%, while in ovulation promotion cycles with an average number of oocytes retrieved is 5

The egg utilization rate is high.

To sum up, the number of eggs taken should be appropriate, rather than simply pursuing quantity. With the development of IVF technology and changes in concepts, doctors no longer blindly pursue the number of eggs retrieved, but are committed to obtaining numbers

The right amount of high-quality eggs can not only avoid adverse effects on the mother, but also reduce waste of biological resources, and help achieve better pregnancy results.

2. What is the success rate of test tube?

Quality of semen


Semen

is one of the two key components of a successful embryo, and its quality is crucial. Sperm number and motility directly affect the fertilization of eggs. If the sperm count per cc in semen is less than

If the activity is less than 30%, IVF technology is recommended and is not suitable for artificial insemination; if the activity is less than 5 million per cc or the activity is less than 20%, IVF is also recommended

If there are less than 1 million animals per cc or activity is less than 10%, ICSI (Single Sperm Microinjection) IVF technology is needed.

Quality of the egg

Women's age is negatively correlated with egg quality. The older the age, the worse the egg quality. For women over 35 years old, the quality of their eggs begins to age; for women over 38 years old, 40 

is over the age of age, so it is necessary to take ovarian protection measures or use advanced ovarian resuscitation technology to improve egg quality.

Quality of the embryo

Even if the quality of eggs and sperm reaches the standard, the quality of the formed embryo may not be ideal. Embryo quality is an important factor affecting the success rate of IVF. High-quality embryos are more likely to be successfully conceived, while low-quality embryos are the opposite

. In general, the pregnancy rate for three high-quality embryos is 25% - 30%. But it also increases the risk of multiple births accordingly. Quality embryos come from quality

Eggs, sperm and stable laboratory culture system. Therefore, the third generation of IVF technology focuses on genetic screening before embryo transfer. By selecting healthy over-tested blastocysts for transfer, it can improve the efficiency of

Success rate.

Embryo implantation surgery

After going through processes such as ovulation, sperm collection, and embryo culture, embryo transfer has become a key link. Accurately place the embryo in a position that is easy to implant, until the endometrial thickness reaches 8 

- 12mm, rich blood flow, good endometrial cell division, and balanced endocrine levels

Quality of the endometrium

The endometrium is the place where the embryo is implanted. When its thickness is appropriate, blood flow is abundant, and cells divide well, on the contrary, if the endometrium is too thin, blood flow is insufficient, or hormones are secreted

Lack is not conducive to embryo implantation. During embryo implantation, the uterus may contract, and sometimes the embryo may even be pushed into the fallopian tubes, causing ectopic pregnancy, with an incidence of about 5 - 7%. Due to

After embryo implantation, the patient should have adequate bed rest and sufficient lutein should be replenished

Your feelings

Excessive psychological stress can affect endocrine levels, which in turn has an adverse impact on the success rate of IVF. Excessive psychological stress can cause nervous tension in women, causing disorder of uterine muscle contraction, and causing the embryo to have no

The normal implantation method eventually led to the failure of IVF embryo transfer. When women are under stress for a long time, it will seriously interfere with the endocrine system, and emotions have a significant impact on pregnancy. This is also the reason why some women

are experiencing stress

.

The reason for unexpected conception after God relaxed.

Combining the above factors, we can see that the success rate of IVF does not depend on the number of eggs retrieved, but is closely related to many factors such as sperm and egg quality, uterine environment, and emotion.


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