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Will the health of children born of frozen embryos be affected?
Source: LelaiwaPublished: 2024-12-17
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At present, embryo freezing technology has developed relatively mature as a fertility preservation method. In addition to being carried out in vitro during the early embryonic development stage, IVF technology is similar to nature in other aspects

.

There are many similarities to conception. In 2012, New England magazine published a large sample study. The study looked at the health status of 308974 children born in South Australia

Statistics include 6163 children born through assisted reproductive technology. After removing the influencing factors of the parents themselves, it was found that in vitro fertilization (IVF, commonly known as the first generation of test-tube babies) children

The risk of birth defects is similar to that of natural pregnancy; the risk of birth defects in the offspring of the fresh embryo transfer cycle of oocyte single sperm injection (ICSI, commonly known as the second generation of test-tube babies) is slightly higher than that of natural pregnancy

However, the risk of birth defects in the offspring of the frozen embryo transfer cycle did not increase.

This is mainly because after controlled ovarian hyperstimulation, the expression of estradiol and progesterone receptors on the endometrium will be significantly changed, which will significantly advance the development of the endometrium, thus reducing the risk of embryonic growth.

The probability of lying in the uterus. Therefore, the clinical pregnancy rate of fresh embryo transfers is lower than that of frozen embryo transfers. Secondly, during the freeze-resuscitation process, the difference between high-quality embryos and abnormal embryos will become more obvious

Abnormal embryos will be eliminated, thereby reducing the rate of birth defects in the fetus. Moreover, the appropriate cycle can be selected for frozen embryo transfer. Compared with fresh embryo transfer,

Some studies have shown that newborns born with frozen and thawed embryo transfer have significantly lower body weight rates, probability of prenatal bleeding, perinatal premature birth and mortality rates than freshly transplanted embryos. However

However, frozen embryos are mainly targeted at infertile couples undergoing IVF, and are generally not used as a means for normal people to preserve their reproductive functions. Clinical trials have proved that new

There are no differences in listening and speaking abilities and nervous system development among children. Judging from the long-term follow-up of the descendants of frozen embryos at home and abroad, the growth, development and health status of children born with frozen embryos


There is no significant difference between children born with fresh embryos in terms of

and immunity levels, and there is no physical or intellectual disadvantage.

Therefore, frozen embryos are still unable to replace fresh embryos. As of now, people born using embryo freezing technology have just passed the age of 40, and its safety will require longer follow-up verification. Currently make

The freezing methods used can minimize damage to cells and ensure cell survival. Embryo freezing technology usually uses vitrification freezing, which can greatly avoid intracellular ice

The production of crystals allows most of the embryos to survive completely after resuscitation.

Studies have shown that compared with fresh embryos, frozen embryos have similar implantation ability in the uterus during embryo transfer. It can be seen that there is still a high probability that frozen embryos or blastocysts will be

Survive, implant, and develop into a healthy fetus. At the same time, theoretically speaking, freezing cells does not change the genetic material within the cells.


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