Embryos can be divided into cleavage stage embryos and blastocysts based on different culture time, and can be divided into fresh embryos and frozen embryos based on whether the embryos have been frozen. Normally, after in vitro fertilization of eggs and sperm

The formed fertilized egg continues to divide into blastomere. By day 3, an embryo consisting of 5 to 10 blastomere will be formed. This is called a cleavage stage embryo, also known as an early embryo. And in the early days

Based on the embryo, the embryo continues to be cultured in vitro. After 5 to 6 days, the blastocyst cavity will develop. The embryo at this stage is called a blastocyst. If the cleavage stage embryo and blastocyst are female

If the body conditions are not suitable for transplantation, they are stored in liquid nitrogen at-196℃ through freezing technology. Such embryos are called frozen embryos. Frozen embryos can be implanted into the uterine cavity after thawing to increase the probability of conception

What rate.

Is the cleavage stage embryo on day 3 transferred or the blastocyst transferred? This requires in-depth analysis based on the specific conditions of each patient. If a woman has an endometrial thickness of 8 to 15 during the month of ovulation induction, 

If estrogen and progesterone are within the appropriate range between millimeters and there are no discomfort caused by promotion of expulsion, you can choose to transfer fresh cleavage stage embryos or blastocysts in the month of egg retrieval. For

For patients with problems such as insufficient or too thick endometrial thickness, uneven endometrial thickness, polyps, and inappropriate estrogen and progesterone levels, it is recommended to freeze all embryos in-

In liquid nitrogen at 196 ° C, when the hormone levels and intimal conditions of the female patient are more suitable in the later stage, the appropriate timing will be selected based on the type of frozen embryo for embryo transfer.

Given the distinction between cleavage stage embryos and blastocysts, what is the essential difference between the two? What conditions are suitable for blastocyst culture? As mentioned earlier, cultivating blastocyst is based on the cleavage stage embryo

The further culture process of embryos. From a theoretical perspective, during this process, lower-quality embryos will be screened out under in vitro conditions, stopped developing, or eliminated due to poor quality.

In other words, the blastocyst is the product of further screening and can develop to the next stage, so its quality is naturally relatively high. Therefore

stage embryos. The success rate of blastocyst cultivation on day 3 was higher for embryos with better quality than for embryos with worse quality. In addition to the higher quality of embryos, blastocyst transfer is more in line with the implantation period, so

Transplanted blastocysts have a lower probability of ectopic pregnancy than transferred cleavage stage embryos.

At present, many reproductive centers generally recommend that women who have a second child, a scarred uterus, a small uterus, and low height, in order to reduce the adverse effects of having twins or multiple pregnancies.

embryos don't have to worry too much. In fact, doctors in reproductive centers usually make comprehensive considerations based on the patient's physical conditions and provide an appropriate transplant plan. Although the success of blastocyst transfer

However, not all patients are suitable for blastocyst cultivation. Because during the blastocyst culture stage, some low-quality embryos are at risk of failure to cultivate blastocyst

For some patients with small number of embryos or deviation in embryo quality, cultivating blastocysts in this case may lead to the situation that no embryos can be utilized in the end. And it is not the cleavage stage embryo on day 3

It will not succeed after the transplant. Therefore, when weighing the question of whether blastocyst culture should be carried out on the third day of cleavage stage, comprehensive consideration must be made based on the quantity and quality of embryos to avoid erroneous decisions

The policy resulted in the situation where no embryos could be transplanted.

In general, for patients with relatively young age and good ovarian reserve function, it is recommended to raise blastocysts if the number of embryos is large; for patients with repeated implantation failure, it is also recommended to carry out if the number of embryos is large.

Blastocyst culture; blastocyst culture can also be performed in patients with chromosomal abnormalities that require pre-implantation genetic screening because blastocyst culture can cause chromosomal abnormalities or single genes

Patients with genetic diseases provide a certain amount of time for pre-implantation genetic screening.

There is no final conclusion as to which is better to transfer fresh embryos, frozen embryos, or blastocysts. Each transplantation method has its own advantages and disadvantages, and the specific method to choose needs to be determined according to the patient's physical conditions. Build

Suggest patients listen to their doctor's advice before making a choice.

If the patient was unable to obtain high-quality embryos in the previous culture cycle, or repeated non-implantation after multiple embryo transfers or the embryos stopped developing, there is no need to be discouraged. Doctors will help patients

Carefully and comprehensively analyze the reasons for the above situation and make targeted preparations in the next cycle. By improving the quality of sperm and eggs and replacing more suitable ovulation promotion protocols and fertilization methods

Choose the appropriate transplant time, prepare the endometrium before transplantation, and deal with possible factors that may cause the embryo to stop developing in advance, so as to be prepared and improve the ability to perform IVF again

The success rate of assisted pregnancy.