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Shanghai City No. 1 Maternal and Infant Health Center
Since the 1980s, the Department of Assisted Reproductive Medicine has taken the lead in using domestic drugs to jointly induce ovulation in the treatment of infertility under the leadership of the lat…
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The Reproductive Endocrinology Department of Reproductive Medicine Center of the First Maternal and Infant Health Hospital of Shanghai City has accumulated rich clinical experience in assisted reproductive treatment of reproductive endocrine diseases and infertility.

Thereare three characteristic directions for department diagnosis and treatment:

(1) Assisted pregnancy treatment for irregular menstruation and infertility caused by endocrine and metabolic diseases: including polycystic ovary syndrome (PCOS), early-onset ovarian dysfunction, ovary

Decreasedreserve function, irregular menstruation, amenorrhea, dysmenorrhea, hyperprolactinemia, thyroid dysfunction, adrenal disease, obesity, malnutrition, diabetes, metabolicsyndrome

Symptoms and other diseases

(2) Repeated embryo implantation failures: including poor quality of sperm, eggs and embryos, thin endometrium, and abnormal peristalsis of the endometrium, etc.

(3) Fertility evaluation and preservation: including ovarian tumors and breast cancer, lymphoma, leukemia, rheumatic immune diseases, etc. before chemotherapy and radiotherapy.

Thedepartment has 2 chief physicians and 1 deputy chief physician, including 1 doctoral supervisor and 2 master's supervisor at Tongji University. It has strong scientific research and teaching capabilities. Near 5

Published 18 SCI papers as the first author/corresponding author, and won 2 National Natural Science Foundation of China, 5 topics at or above the bureau level, scientific research funding of 2.65 million yuan, and graduated 7

First name.
The department provides one-stop diagnosis and treatment services for infertile patients such as PCOS and obesity, including weight loss, ovulation monitoring, ovulation promotion, artificial insemination and assisted reproductive treatment; to ensure high safety

Develop individualized infertility diagnosis and treatment strategies with the goal of efficiency and speed; carry out a multidisciplinary joint diagnosis and treatment model to provide high-quality science education, exercise, nutrition

and

psychological guidance

.

And psychological guidance as well.

Thereare currently 72 medical staff, including 1 member of the Standing Committee of the Reproductive Medicine Branch of the Chinese Medical Association, 1 member of the National Key Project Chief (Young) Scientist, and 1 member of the National Natural Science Foundation of China.

There are 9 chief medical (technical) divisions, 9 deputy chief medical (technical) divisions, 1 researcher, 1 associate researcher, 3 doctoral tutors, and 9 master's tutors. Clinical medicine

Technicians basically have master's degrees or above, including 31 doctoral students. Open reproductive andrology, reproductive genetic counseling, traditional Chinese medicine assisted pregnancy, infertility, repeated planting failure

PCOS pregnancy assistance, fertility preservation, reproductive endocrine and other specialized diseases clinic. In 2021, 7341 egg retrieval cycles will be completed, with more than 200,000 outpatient visits.
In the past 5 years, he has published 61 papers, including 17 SCI papers, 18 topics at or above the bureau level, and scientific research funding of 11.627 million yuan: 6 projects from the National Natural Science Foundation of China, outstanding youth

There are 1 medical talent training plan, 1 Venus Project, 2 invention patents, and 2 utility model patents.

1,1,2,2.He took the lead in formulating the "Operation Guidelines for ICSI" of the Chinese Medical Association. Wei

Regarding the issue of infertility and abnormal development of gametes and early embryos, it has received support from many national, provincial and ministerial projects. Early mammalian embryonic development was first reported in 2016

The process of establishing histone modification during the breeding process; and using microgenomic technology to reveal the key molecular mechanism of blocking the development of cloned embryos; revealing the abnormality of the zone pellucida leading to infertility

Mechanisms and improves the development of short-term fertilized embryos. Relevant results have been published in journals such as Nature, Cell Stem Cell, Human Genetics, and Fertility and Sterility.

Theresearch results were selected into the "Top Ten Advances in the Field of Life Sciences in China" of China Association for Science and Technology in 2016. The semen analysis in the andrology laboratory obtained the quality control certificate of the German Andrology Society.

Thedepartment provides patients with personalized treatment plans and more intimate, heart-warming and comfortable services to help patients realize their dreams as soon as possible.

Introduction to the test tube process of a woman and infant in Shanghai

1. Pre-processing

stage
Before conducting test tubes, a series of pretreatment work is first needed.
Beforeconducting test tubes, a series of pretreatment work is first needed. This stage mainly includes the following aspects:
n1.‍ Physical examination: Conduct a detailed physical examination on both couples to determine whether there is any infertility problem.


2. Sperm analysis: The man's semen is tested and analyzed to assess whether the quality and quantity of his sperm meet the standards.


3. Ovarian assessment: Assess the woman's ovarian function and ovulation through ultrasound and other methods.


4. Uterine evaluation: Assess the shape and thickness of the woman's uterus through ultrasound and other methods.‍


2. Ovulation induction stage
After the pretreatment stage, if the physical condition of both couples meets the requirements, they can move to the next step-the ovulation induction stage. The main purpose of this stage is to promote

Ovulations into the woman's ovaries multiple times increase the chance of conception. The specific steps are as follows:
n1.‍ Daily injection: Take the injection according to the dose and time prescribed by the doctor.

2. Ultrasound examination: Ultrasound examination was performed at regular intervals to observe follicular growth and endometrial thickness and other indicators.


3. Artificial control of ovulation: When the follicle develops to the appropriate size, an injection is used to urge it to mature and the ovulation time is artificially controlled‍.

3. Oocyte retrieval and semen

processing


After the woman successfully completes ovulation induction, she can enter the process of egg retrieval and semen processing.
After the woman successfully completes ovulation induction, she can enter the process of egg retrieval and semen processing. This process mainly includes the following steps:

t1.‍ Oocyte retrieval: Use ultrasound-guided fine needle aspiration to extract mature follicles.

2. Sperm processing: Centrifuge, wash and other treatments on the semen collected by the man to improve the quality and quantity of sperm.

3. Artificial insemination: Put washed sperm and eggs together and promote fertilization through artificial insemination technology.‍

4. Embryo culture and transfer
After artificial insemination, the egg will gradually develop into an embryo. The next stage is embryo culture and transfer:

t1.‍ Embryo culture: Transfer the fertilized egg into a test tube for culture and observe its development.

2. Frozen preservation: If there are multiple healthy embryos, you can choose to freeze them for subsequent use.

3. Embryo transfer: Transfer healthy embryos into the woman's uterus at the right time point for pregnancy.‍

TIPS:
IVFtechnology is a complex and difficult fertility treatment method. Shanghai First Maternal and Infant Hospital has rich test tube experience and professional medical team, giving couples all-round and intimate attention and guidance throughout the process. Hope that through this article, more couples who need IVF have a deeper understanding of this process.

tHospital address:

1. Address of Shanghai City No. 1 Maternal and Infant Health Center (West Hospital): No. 536 Changle Road, Jing 'an District, Shanghai City

2. Transportation Guide for the First Maternal and Infant Health Hospital of Shanghai City (West Hospital):

Crossingline:

1. Bus Line

Take No. 94, No. 146, No. 26, No. 104, No. 24, No. 41, No. 955, No. 01, No. 127, No. 48, No. 71, No. 925, No. 936, Shanghai-Qingying Special Line, Shanghai-Qingying Special Line

Line, Shanghai-Zhu Special Line, No. 167, No. 198, No. 42, No. 911, No. 911, No. 920, No. 926, No. 49 and No. 45 can reach the hospital.

2. Subway Line


Take
Metro Lines 1, 10, and 12 to South Shaanxi Road Station and get off

Ifyou want to learn more about the multinational assisted reproduction program, you can also contact the customer service ofShanghai City First Maternal and Infant Health Centerfor free consultation. Customer service phone:18101365219

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